Recently, we encountered patients with Meniere's disease (MD) and internuclear ophthalmoplegia (INO) who also showed the discordant patterns of horizontal-torsional nystagmus. Since then, we began to search for discordant horizontal-torsional nystagmus in patients with acute vestibular disorders. This study aimed to determine the
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A lesion in the medial longitudinal fasciculus (MLF) causes internuclear ophthalmoplegia (INO). Many intracranial lesions, such as multiple sclerosis or vascular disorders may be associated with INO; however, INO is a rare complication of minor head injury. The mechanism underlying injury to the MLF may be shear force on the brain stem during
Internuclear ophthalmoplegia (INO) is an eye movement disorder characterized by slowed adduction of the eye on the affected side on horizontal saccades. It is often accompanied by dissociated horizontal nystagmus of the fellow eye and is caused by a lesion in the medial longitudinal fasciculus (MLF) [ 1 ].
Internuclear ophthalmoparesis (INO) in multiple sclerosis (MS) is due to demyelination of the medial longitudinal fasciculus (MLF) and provides an accessible model for studying consequences of raised body temperature and fatigue on central demyelination. 1, 2 Prompted by one of our patient's report of vision improvement after initiating dalfampridine, a potassium channel blocker prescribed
Internuclear ophthalmoplegia (INO) is a rare disorder of conjugate lateral gaze that has been described in a number of neurologic conditions including multiple sclerosis, stroke and less commonly brain tumors. We describe a series of 3 boys (11, 12, 15 years) diagnosed with primary central nervous system tumors (pilomyxoid variant astrocytoma, anaplastic oligoastrocytoma, gliomatosis cerebri
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Internuclear ophthalmoplegia (INO) is a manifestation of intrinsic brainstem disease. It is caused by a lesion involving the medial longitudinal fasciculus between the abducens and oculomotor nuclei.
Internuclear ophthalmoplegia (INO) secondary to cocaine induced ischemic stroke is a rare event with few reported cases in the literature. Diaz-Calderon et al. and Strupp et al. report two similar cases; however, neither is identical to our patient [ 1, 2 ]. The pathogenesis of cocaine induced stroke is controversial but likely is secondary to
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